Wednesday March 23, 2011
Chairs: John A. Kanis and Cyrus Cooper

Refresh calendars
SessionRoom
08:30
09:15
Invited Lecture 5
Human skeletal (stromal) stem cells and control of bone formation (M. Kassem)
09:15
10:15
Selected Oral Presentations
09.15-09.30 PC-OC18
Inhibition of ALK3(BMPRIA) signaling using RAP-661, a novel soluble BMP antagonist, decreases sclerostin expression and increases bone mass - A. Mulivor, Y. Kawamoto, R. Steeves, R. Kumar, J. Seehra, E. Canalis, R.S. Pearsall, N. Solban

09.30-09.45 PC-OC19
Serum leptin and bone mass density in postmenopausal osteoporotic females of pakistan - M. Lateef, M. Baig, A. Azhar

09.45-10.00 PC-OC20
Cartilage-specific deletion of PPAR-gamma in mice results in early endochondral bone defects and accelerated aging- dependent development of osteoarthritis - R. Monemdjou, F. Vasheghani, G. Perez, J-P. Pelletier, J. Martel-Pelletier, M. Kapoor

10.00-10.15 PC-OC21
PTH efficacy in bone healing models with T-cell deficient rats - M. Sato, M. Adrian, M. Hamang, A. Harvey, Q. Zeng, Y. Ma
10:15
10:45
Coffee Break
10:45
11:30
Invited Lecture 6
Post-natal, microvascular niches of skeletal, non-skeletal and hematopoietic stem cells (P. Bianco)
11:30
12:30
Selected Oral Presentations
11.30- 11.45 PC-OC22
Pharmacological intervention on spontaneous osteoarthritis in STR/ort mice: effects of aggrecanase or COX-2 inhibition - R. Chiusaroli, A. Giordani, I. Verpilio, S. Mandelli, M. Lanza, G. Caselli, L. Rovati

11.45-12.00 PC-OC23
MHC class II transactivator: a novel regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity - S. Cenci, R. Sitia, W. Reith, E. Benasciutti, E. Mariani, E. Perilli, E. Barras, N. Fazzalari, L. Otten, H. Acha-Orbea, R. Faccio

12.00-12.15 PC-OC24
Iron overload stimulates osteoclast differentiation of murine osteoclast progenitor RAW 264.7 through the production of reactive oxygen species - J. Peng, X. JIa

12.15-12.30 PC-OC25
Strontium ranelate inhibits key factors affecting bone remodelling in human osteoarthritic subchondral bone osteoblasts - J. Martel-Pelletier, S. Kwan Tat, F. Mineau, J. Caron, J-P. Pelletier
12:30
14:00
Poster Viewing
14:00
14:45
Invited Lecture 7
Control of bone formation (T. Schinke)
14:45
15:45
Selected Oral Presentations
14.45-15.00 PC-OC26
An acidic microenvironment enhances myeloma growth but triggers anti-tumor and anti-resorptive activity of reveromycin A - M. Abe, S. Fujii, K. Takeuchi, S. Ozaki, M. Kawatani, H. Osada, E. Tanaka, T. Matsumoto, K. Watanabe, C. Qu, M. Hiasa, A. Nakano, T. Harada, S. Nakamura, H. Miki, K. Kagawa

15.00-15.15 PC-OC27
PTH activates pKC via plc-independent signalling pathway: Fret analysis - J. Li, R. Feng, W. Yan, J. Jiang, J. Chen, J. Guo, F.R. Bringhurst, D. Yang

15.15-15.30 PC-OC28
Pharmacology of STR/ort mice as an osteoarthritis model: responsiveness to ep4 antagonists and aggrecanase inhibitors - R. Chiusaroli, P. Larger, C. Falcioni, A. Grotti, M. Lanza, L. Stasi, L. Rovati, G. Caselli

15.30-15.45 PC-OC29
Characterization and mechanism of action of new experimental model of osteoporosis in TALLYHO/jngj male mouse: the potential of mouse for the study of male osteoporosis - M.A. Bae, J.S. Song, H.Y. Won, E.S. Hwang
15:45
16:30
Invited Lecture 8
Regulation of bone mass by serotonin (G. Karsenty)
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