Tuesday March 22, 2011
Chairs: Gerard Karsenty and René Rizzoli

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SessionRoom
08:30
09:15
Invited Lecture 1
Bone development, inflammation and the role of Fos for proteins (E. Wagner)
09:15
10:15
Selected Oral Presentations
09.15-09.30 PC-OC1
DLK1/FA1 regulates the early chondrogenesis during embryonic endochondral bone formation process and its expression is modulated by tgF-B1 signaling pathway - B. Abdallah, L. Harkness, H. Taipaleenmaki, M. Kassem

09.30-09.45 PC-OC2
Genetic variation in the Lrp4 gene influences bone mineral density and hip geometry while missense mutations cause sclerosteosis - E. Piters, M. Andersen, K. Wraae, K. Brixen, M. Kneissel, W. Van Hul, E. Boudin, O. Leupin, F. de Freitas, K. Jennes, M. Bueno-Lozano, F. Ramos-Fuentes, P. Itin, T.L. Nielsen

09.45-10.00 PC-OC3
Regulatory loops involving igfbp5 account for a fine tuning regulation of osteoblast activity - B. Peruzzi, A. Cappariello, A. Del Fattore, N. Rucci, F. De Benedetti, A. Teti

10.00-10.15 PC-OC4
Osteoid osteoma is an osteocalcinoma affecting glucose metabolism - C. Confavreux, O. Borel, F. Lee, G. Vaz, M. Guyard, M-C. Carlier, C. Fadat, R. Chapurlat, G. Karsenty
10:15
10:45
Coffee Break
10:45
11:30
Invited Lecture 2
Local regulation of bone and fat homeostasis by Fra-1, a member of the aP-1 family of transcription factors (J.-P. David)
11:30
12:30
Selected Oral Presentations
11.30-11.45 PC-OC5
Sclerostin antibody treatment enhances fracture healing and increases bone mass and strength in non-fractured bones in an adult rat closed femoral fracture model - C. Li, H. Tan, M. Barrero, E. Lee, F. Asuncion, M. Ominsky, H. Ke

11.45-12.00 PC-OC6
Genome wide association study identifies seven loci that account for 86% of the population attributable risk of paget’s disease of bone - O. Albagha, W. Fraser, L. Gennari, M. Hooper, W. Van Hul, G. Isaia, G. Nicholson, S. Papapoulos, J. del Pino Montes, R. Gonzalez-Sarmiento, M. di Stefano, S. Wani, J. Walsh, S. Ralston for the GDPD Consortium, M. Visconti, N. Alonso, K. Goodman, M.L. Brandi, T. Cundy, R. Dargie, A. Falchetti

12.00-12.15 PC-OC7
Si-hydroxyapatite with covalently linked or adsorbed osteostatin exhibits improved osteogenic capacity in osteoblastic cells - D. Lozano, M. Manzano, D. Arcos, S. Portal-Núñez, P. Esbrit, M. Vallet-Regí

12.15-12.30 PC-OC8
Psoralen stimulates osteoblast differentiation by activation of bone morphogenetic protein signaling - D. Tang, F. Yang, Z. Yang, J. Huang, Q. Shi, D. Chen, Y. Wang
12:30
14:00
Poster Viewing
14:00
14:45
Invited Lecture 3
The osteoclast in tumoral bone involvement (A. Teti)
14:45
15:45
Selected Oral Presentations
14.45-15.00 PC-OC9
MicrorNA-138 targets focal adhesion kinase and regulates In Vivo - T. Eskildsen, H. Taipaleenmäki, J. Stenvang, B. Abdallah, N. Ditzel, S. Kauppinen, M. Kassem

15.00-15.15 PC-OC10
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor - A. Rauch, U. Baschant, M. Rauner, M. Amling, L. Hofbauer, K. De Bosscher, J. Tuckermann

15.15-15.30 PC-OC11
TNFrSF11A gene allelic variants are associated with paget’s disease of bone and interact with SqStM1 mutations to cause the severity of the disorder - D. Merlotti, D. Formicola, A. Mingione, P. Fenoglio, A. Criasia, R. Muscariello, P. Strazzullo, G. Isaia, R. Layfield, R. Nuti, F. Gianfrancesco, L. Gennari, D. Rendina, M. Di Stefano, G. Mossetti, S. Gallone, T. Esposito, S. Magliocca, A. Goode

15.30-15.45 PC-OC12
Strontium ranelate reduces adipogenic differentiation of bone marrow mesenchymal stromal cells and reverses the excessive bone marrow adipogenesis in senescent osteopenic mice - Z. Saidak, E. Haÿ, C. Marty, A. Barbara, P. Marie
15:45
16:30
Invited Lecture 4
Pathophysiology if tumoral bone disease (Ph. Clézardin)
16:30
17:30
Selected Oral Presentations
16.30-16.45 PC-OC13
Association of serum sclerostin with bone turnover, endogenous hormones, bone mineral density (bMD) and fracture risk in postmenopausal women. the ofely study - P. Garnero, E. Sornay-Rendu, F. Munoz, O. Borel, R. Chapurlat

16.45-17.00 PC-OC14
The response of osteocytes to mechanical loading and osteocyte signalling towards osteoclasts are positively affected by strontium ranelate - J. Klein-Nulend, B. Zandieh-Doulabi, A. Bakker

17.00-17.15 PC-OC15
Control of bone resorption by semaphorin 4D is dependent on ovarian function - I. Machuca-Gayet, R. Dacquin, C. Domenget, P. Jurdic

17.15-17.30 PC-OC16
An antagonist of interleukin-15 inhibits weight and bone loss in a mouse model of inflammatory bowel disease - D. Pierroz, S. Ferrari-Lacraz, X. Zheng, S. Ferrari
17:30
19:00
Meet The Faculty
How to write a grant (C. Cooper) / How to write a manuscript (G. Karsenty) / How to build up a lecture (E. Wagner) / Women in academic careers (A. Teti)
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